Tuesday, March 10
Tirzepatide Mechanism of Action (MOA)
Tirzepatide (Mounjaro®, Zepbound®) is a first-in-class, dual agonist of the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. Its mechanism of action is unique because it integrates the effects of both incretin hormones into a single molecule, leading to improved blood sugar control and significant weight loss .